Podiatrist in Sorrento Valley, CA

From vaccine development to tissue engineering and gene editing to cell therapies, recent discoveries in biotechnology are rapidly transforming the way the world approaches healthcare. Beyond medical advancements, biotech—an industry based on using biological processes to develop technologies and products—has also made waves in agriculture, fuel manufacturing, environmental protection, and the scale-up methodology world of chemical engineering.

Much of the growth in biotech has taken place in the San Diego area, which has been recognized as the third-largest hub for the industry in the nation. Locally, this development has led to the creation of many local jobs, which has only continued to make this Southern California hotspot even greater.

The industry’s presence is significant in Sorrento Valley, as this laidback, welcoming community is conveniently close to UCSD and other universities, as well as numerous life sciences companies. By taking a closer look at the top biotech companies in Sorrento Valley, it’s easy to understand the excitement behind the industry—and the opportunities it offers to current and future residents.

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Top Biotech Companies in Sorrento Valley CA

Since the industry has such a wide reach in terms of commercial applications, biotech companies in Sorrento Valley, CA are working on many different projects. Whether you’re curious about biotech discoveries in general, are exploring investment opportunities, or want to become a life sciences professional, this list of San Diego biotech companies can help shed more light on what’s happening—and where significant growth is occurring.

As a leader in mRNA production, TriLink Biotechnologies has played a major role in the development and production of COVID vaccines. They have also partnered with the Department of Defense to help improve pandemic responses in the future. Beyond these developments, the company also contributes to advancements in gene editing, cell therapy, and epigenetics. With recent expansion in their R&D department, TriLink continues to create jobs and offer many attractive benefits to employees.

Recently acquired by Thermo Fisher Scientific, Mesa Biotech Inc. is a growing life sciences company. The Accula SARS-CoV-2 Test is Mesa Biotech’s most recent notable development, offering PCR test results in about 30 minutes to help individuals diagnose COVID infections—even when small levels of the virus are present. Hiring is optimistic at Mesa Biotech and the company maintains a 4-star rating from employees on Glassdoor.

Genlantis is a small biotech firm in Sorrento Valley that is regarded for its contributions in biologic reagents. Their focuses are on protein expression systems within proteomics and transfection applications. While the company is smaller than other life science companies, employees have rated it 5 stars on Glassdoors, citing freedom in the office as a benefit.

Inscripta Inc. is regarded for its Onyx® Platform—a push-button solution for rapid microbial strain optimization. This tool simplifies scalable CRISPR-based genome engineering with design and analysis software and fully-automated capabilities. As an employer, Inscripta is recognized for providing a modern work environment that prioritizes diversity, innovation, and integrity.

Based in Sorrento Valley, LeGene Biosciences specializes in enzyme research, development, and manufacturing. The biotech company’s high-quality, great-value reagents and kits are used globally for life science and pharmaceutical applications. The team is also recognized for taking a collaborative, personalized approach with clients to achieve notable results.

Operating a cGMP facility in Sorrento Valley, Allele Biotechnology has made many great strides in molecular biology research over the years—such as those in fluorescent proteins, iPSCs, gene editing, and RNA interference. The company’s nanoantibody and cell therapy applications—including those used for COVID-19 purposes—are disruptively state-of-the-art and aid in lower production costs in therapeutics. Backed by a strong management team and scientific advisory board, Allele Biotechnology offers attractive employment opportunities geared to help people grow at every stage of their careers.

Angiocrine Bioscience is dedicated to improving patient lives through its E-CEL® products. Developed from years of forward-thinking research, these solutions are based on the body’s natural processes to repair and heal tissues and organs. While the company started in NYC, it relocated to San Diego to be a part of the leading biotech companies in Sorrento Valley that focus on regenerative sciences. Angiogrine Bioscience prides itself on its bright multi-disciplinary team that offers opportunities for employees to use creativity and self-motivation to develop life-changing treatments for patients.

Organovo is a biotech company in San Diego that’s pioneering the way 3D bioprinting is used in healthcare. Their developments are used to develop 3D tissues that imitate human biology, making it easier to understand the ways diseases impact the body, and in turn, refine treatments to address their effects. On Glassdoor, employees celebrate the company’s start-up environment and inclusivity as values that help them contribute and learn.

Closing Thoughts

A quick look at the leading biotech companies in Sorrento Valley showcases the potential that this evolving industry offers the local community, professionals, and the globe. Keeping track of these and other organizations is a great way to better understand the way their discoveries are being applied and the economic opportunities they hold. Many of these companies are also eager to recruit new talent—including interns from universities—so those interested in working in biotech are encouraged to reach out to the facilities that attract their interest.

The banner image of a biomed property located within the Sorrento Valley biotech submarket is courtesy of BioMedRealty.com

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SAN DIEGO — The popular sports entertainment brand Topgolf announced Thursday their plans to open not one, but two locations in San Diego.

In addition to the plans to build a Topgolf location on the San Diego waterfront, the company is now adding plans to open a driving range in Sorrento Valley.

In July, Topgolf entered into exclusive negotiations with the Port of San Diego to bring one of their high-tech driving ranges to East Harbor Island, although it has several steps to go through before being approved and cleared to break ground at that location, Brianne Mundy Page with the Port of San Diego told FOX 5 via email.

“It’ll be at least a couple years before construction could begin, but likely longer. The timeline is dependent on various approvals by the Port of San Diego Board of Port Commissioners, real estate negotiations, environmental review, drafting and issuing a Coastal Development Permit, construction schedule, etc.,” Mundy Page stated.

The newly announced Sorrento Valley location plans to redevelop the Carroll Canyon Golf Center, according to a news release from Topgolf. The planned range will feature three levels and over 80 hitting bays.

“We’ve wanted to bring the Topgolf venue experience to San Diego for a long time, and it’s encouraging to see us making progress toward that goal,” said a quote attributed to Topgolf Chief Development Officer Chris Callaway. “While still in the early stages, we’re excited by the potential to bring even more play to the San Diego community.”

While the exact location for the East Harbor Island is yet to be determined, the brand, owned by Carlsbad-based Callaway Golf, was given tentative approval by Port of San Diego commissioners to move ahead with the potential $40 million facility. The company’s plan calls for a 68,000-square-foot building on an 8.5-acre site with over 100 hitting bays as well as a restaurant and a bar.

The back-to-back storms that hit over the weekend produced more rain than anticipated in many areas and wind gusts upwards of 30 mph at the coast and 70 mph inland

Jan. 16, 2023 Updated 7:15 PM PT

Swift-water rescue crews guided 11 people to safety Monday across San Diego County where back-to-back storms over the holiday weekend drenched a region that was already saturated from a series of storms dating to mid-December.

The lower San Diego River in Mission Valley quickly reached flood stage, spilling water onto streets next to the Fashion Valley Mall while football-field-sized ponds formed along Escondido Creek near Encinitas. The rain also caused massive boulders to tumble onto State Route 94 east of Jamul.

The latest storm arrived late Sunday and lasted into Monday, packing fierce winds that appear to have contributed to significant power outages. About 14,000 San Diego Gas & Electric customers lost electricity in Coronado and other parts of the county.

The winds gusted to 44 mph at Naval Station North Island, 48 mph at Camp Pendleton and 74 mph at Palomar Mountain. The latter figure is the equivalent of a category one hurricane. The National Weather Service said the winds toppled a large pine tree on apartments on Marathon Drive in Mission Valley, making some units uninhabitable.

During a three-day period ending at 5:04 p.m. Monday, the two storms dropped an extraordinary 11.21 inches of rain on Palomar Mountain, 7.32 inches at Julian and 5.42 inches at Escondido. The totals were expected to rise by Tuesday morning.

The mayhem was caused by the polar jet stream, which has dropped unusually far south in recent weeks, allowing a series of storms to clobber California.

Until Monday, such areas as San Francisco, Santa Cruz and Los Angeles had taken the toughest beatings. But the storms that occurred from late Saturday into Sunday and late Sunday into Monday took unusually straight paths into San Diego County, which was alternately soaked with light, misty rain and wild downpours.

The largest swift-water rescue on Monday involved seven people who became stuck on a small island in fast-moving water near 4700 Pacific Highway in San Diego just after 9 a.m. Some of the victims ended up in the water. Rescue crews quickly moved the people to safety.

About two hours earlier, an unidentified person got caught in swift waters flowing through the Otay Lakes area east of Chula Vista. Cal Fire said they found a vehicle in the water with the victim on top. The person was rescued, assessed and released by paramedic crews.

Later on Monday, the San Diego County Sheriff’s Department aerial unit and Cal Fire San Diego crews worked to find and rescue two men who had climbed trees to escape flooding in a nearby area of the river, close to the 13000 block of Otay Lakes Road, that flows into the Lower Otay Lake, Cal Fire San Diego Fire Captain Michael Cornette said. The men were taken to the hospital and said to be in stable condition.

Earlier in the day, around 6 a.m., a swift-water rescue team rescued a woman whose car entered the San Diego River in Mission Valley near Camino Del Este and Station Village Lane. The driver’s car was in about 2 feet of water when the incident occurred.

That area has received 2 to 3 inches of water over a 24-hour period, and the river was at flood stage — 12.77 feet — at the time, the weather service said.

The storm also triggered a debris flow along State Route 78 east of Julian, blocking both lanes of traffic, the weather service said. A portion of the eastbound highway, from El Camino Real to College Boulevard, was also closed for a couple of hours Monday morning and into the early afternoon because of “extreme flooding,” the California Department of Transportation said. Lanes reopened around 12:50 p.m., the agency said.

Flooding also was a factor in the closure of a portion of Discovery Street in San Marcos, Harmony Grove Road in Escondido and Central Avenue near Bonita. Flooding closed part of a popular horse trail in Carmel Valley.

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Portions of State Route 94 east of Jamul at Otay Lakes Road, Barrett Lakes Road and State Route 188 were closed for several hours on Monday morning after large boulders fell onto the highway overnight, Caltrans said. The stretch of highway was reopened by midday.

The winds also have had an impact.

The weather service said a downed tree slowed traffic at the intersection of Valley Center Road and Mac Tan Road in Valley Center. The area was hit by nearly 2 inches of rain over a 24-hour period and winds gusting nearly 30 mph.

In Scripps Ranch, a tree fell on a car near Pomerado Road and Avenue of Nations at around 10:12 a.m., partially blocking the roadway, police said. The driver, who was not injured, was helped out by a passerby, and the tree was relocated to the south side of Pomerado.

About 14,000 San Diego Gas & Electric customers in Coronado and other communities in San Diego County lost power Monday, the utility reported.

In Coronado, a minor fire at an area substation resulted in 8,835 customers in the northern part of the city losing power for about an hour, SDG&E spokesperson Alex Welling said. Power was restored to all customers in the area by 11:56 a.m., he said.

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Other communities experiencing power outages included Bonita, Carlsbad, Encinitas, Fallbrook, La Mesa, Mission Beach, Oceanside, Ramona and Sorrento Valley, according to the SDG&E outage map.

Rainfall figures are equally eye-catching.

During the three-day period, the two storms dropped 8.47 inches of rain at Lake Cuyamaca, 8.02 inches at Pine Hills, 7.11 inches at Otay Mountain, 6.02 inches at Lake Wohlford and Mount Woodson, 5.65 inches at Mount Laguna, 5.29 inches at Valley Center, 5.08 inches at Alpine, 4.74 inches at Ramona, 4.65 inches at Bonsall, 4.60 inches at Campo, 4.59 inches at Cameron, 4.55 inches at Valley Center, and 4.51 inches at Fallbrook.

The storms also dropped 4.44 inches at Barona, 4.40 inches at La Mesa, 4.34 inches at San Diego Country Estates, 4.18 inches at National City, 4.04 inches at Santee, 3.96 inches at Carlsbad, 3.83 inches at Encinitas, 3.80 inches at San Marcos, 3.64 inches at Oceanside, 3.60 inches at Rancho Bernardo, 3.52 inches at Fashion Valley, 2.68 inches at San Diego International Airport, 2.63 inches at Chula Vista, 2.53 inches at Point Loma, and 0.59 inches at Borrego Springs.

A high surf advisory will be in effect at the coast through 10 p.m. Tuesday. The waves have been slamming local beaches for days.

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“The surf will gradually lower Tuesday night and Wednesday, with no high surf expected the rest of the week,” the weather service said.

Monday, the San Diego County Office of Education announced that schools in five East County districts — Julian Union Elementary School District, Julian Union High School District, Mountain Empire Unified School District, Spencer Valley School District and Warner Unified School District — will be closed on Tuesday because of the extreme weather and hazardous road conditions.

City News Service contributed to this story.

The tour of Italy in the Bay Area continues with host Jessica Wills making a stop at Locanda Sorrento. Watch the clip to see why it’s one of Campbell’s hottest restaurants.

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Since 2020, Justin Gaspar has been quietly supplying some of the region’s best salmon tartines and crunchiest baguettes to some of the area’s top cafes through his wholesale business Hommage Bakehouse. At siblings Willy Wu Jye Hwa and Karine Beers’ La Clochette Du Coin, for example, Gaspar is the head bread supplier. Now, Gaspar is opening a shop of his own in Mission Valley. The flagship location of Hommage Bakehouse will open in the Civita Properties by early summer 2023.

Gaspar says he’s excited have a place Hommage can call home. “Having spaces of our own will allow us to really get to know our fellow San Diegans and reintroduce them to Hommage Bakehouse, separate from its sister company, La Clochette du Coin,” Gaspar wrote in an email to Eater San Diego.

The flagship bakery will open with a focus on seasonal flavors using local produce and will offer an expanded bread and pastry menu. The team is in the experimentation phase for now, though. Ube bibingka (Filipino custard buns) — a sell-out hit when run as a special, Gaspar points out — should make an appearance on the menu and, hopefully, become a regular offering.

The wholesale operations and business as it stands is expanding into a larger facility in Sorrento Valley, complete with its own small retail window. The bakery’s new wholesale space will host a grand opening once final dates are in place. And fans don’t need to worry — La Clochette will continue to receive Hommage bread and pastry daily.

The business is now found in dozens of cafes and restaurants around town, and Gaspar says it’s always a good feeling to walk into the team’s favorite places to see their bread and pastries on the menu. Further details will emerge as the date draws nearer, but for now it’s heads down work time to get everything ready. “We are so excited to grow into a space that can handle our current volume and support the team that has helped us get to this point,” Gaspar wrote.

Hommage Bakehouse will aim to open in early summer 2023 within the Civita Properties in Mission Valley. Expected hours are 9 a.m. to 3 p.m.

Update: October 18, 12:40 p.m.: This story has been updated to reflect that Hommage Bakehouse debuted in August 2020. La Clochette opened in 2015 and Gaspar joined the owners at the end of 2019.

La Clochette Du Coin/Hommage Bakehouse

4680 Cass Street, San Diego, CA 92109

La Clochette Du Coin

4680 Cass Street, , CA 92109 (858) 412-5558 Visit Website

San Diego

, , CA Visit Website